Many people are reporting connectivity problems with USB-C Hubs and macOS Monterey. I have experienced this issue at a local school where I tech support their Macs. The research shows this is not a hardware issue, it is a macOS Monterey problem. This article describes what problems people are experiencing. If you are experiencing this problem, you are not alone. Hopefully, because so many people are having this issue, Apple will get it fixed in the 12.1 update due out soon.